Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/- |
| Location | 1684871..1685285 | Replicon | chromosome |
| Accession | NZ_CP113051 | ||
| Organism | Staphylococcus aureus strain Viktor | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | OS088_RS08630 | Protein ID | WP_025174939.1 |
| Coordinates | 1685034..1685285 (-) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | OS088_RS08625 | Protein ID | WP_000028424.1 |
| Coordinates | 1684871..1685044 (-) | Length | 58 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OS088_RS08565 (1680911) | 1680911..1681378 | - | 468 | WP_000919026.1 | phage terminase small subunit P27 family | - |
| OS088_RS08570 (1681508) | 1681508..1681852 | - | 345 | WP_000817289.1 | HNH endonuclease | - |
| OS088_RS08575 (1681867) | 1681867..1682319 | - | 453 | WP_000406191.1 | nucleoside triphosphate pyrophosphohydrolase family protein | - |
| OS088_RS08580 (1682434) | 1682434..1682904 | - | 471 | WP_000282755.1 | hypothetical protein | - |
| OS088_RS08585 (1682927) | 1682927..1683127 | - | 201 | WP_001570807.1 | DUF1514 family protein | - |
| OS088_RS08590 (1683127) | 1683127..1683252 | - | 126 | WP_031783376.1 | transcriptional regulator | - |
| OS088_RS08595 (1683245) | 1683245..1683448 | - | 204 | WP_001072793.1 | hypothetical protein | - |
| OS088_RS08600 (1683445) | 1683445..1683639 | - | 195 | WP_000141186.1 | hypothetical protein | - |
| OS088_RS08605 (1683636) | 1683636..1683842 | - | 207 | WP_000195826.1 | DUF1381 domain-containing protein | - |
| OS088_RS08610 (1683879) | 1683879..1684412 | - | 534 | WP_025920701.1 | dUTP diphosphatase | - |
| OS088_RS08615 (1684427) | 1684427..1684588 | - | 162 | WP_000889683.1 | hypothetical protein | - |
| OS088_RS08620 (1684589) | 1684589..1684870 | - | 282 | WP_000454994.1 | hypothetical protein | - |
| OS088_RS08625 (1684871) | 1684871..1685044 | - | 174 | WP_000028424.1 | hypothetical protein | Antitoxin |
| OS088_RS08630 (1685034) | 1685034..1685285 | - | 252 | WP_025174939.1 | DUF1024 family protein | Toxin |
| OS088_RS08635 (1685300) | 1685300..1685542 | - | 243 | WP_000131381.1 | phi PVL orf 51-like protein | - |
| OS088_RS08640 (1685546) | 1685546..1685914 | - | 369 | WP_000101275.1 | SA1788 family PVL leukocidin-associated protein | - |
| OS088_RS08645 (1685927) | 1685927..1686331 | - | 405 | WP_000401978.1 | RusA family crossover junction endodeoxyribonuclease | - |
| OS088_RS08650 (1686340) | 1686340..1686558 | - | 219 | WP_000338527.1 | hypothetical protein | - |
| OS088_RS08655 (1686565) | 1686565..1687458 | - | 894 | WP_000148335.1 | DnaD domain-containing protein | - |
| OS088_RS08660 (1687488) | 1687488..1687958 | - | 471 | WP_000934760.1 | single-stranded DNA-binding protein | - |
| OS088_RS08665 (1687959) | 1687959..1688576 | - | 618 | WP_071621397.1 | MBL fold metallo-hydrolase | - |
| OS088_RS08670 (1688657) | 1688657..1689577 | - | 921 | WP_000138475.1 | recombinase RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | scn / sak / sea / hlb / groEL | 1656479..1707920 | 51441 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|