Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2635263..2635542 Replicon chromosome
Accession NZ_CP113049
Organism Staphylococcus aureus strain Ahri

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS089_RS13030 Protein ID WP_001802298.1
Coordinates 2635263..2635367 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2635363..2635542 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS089_RS13000 2630657..2631439 + 783 WP_000908190.1 ABC transporter ATP-binding protein -
OS089_RS13005 2631507..2632364 + 858 WP_000370919.1 HAD family hydrolase -
OS089_RS13010 2632558..2632772 - 215 Protein_2563 exotoxin -
OS089_RS13015 2633059..2633151 - 93 WP_031844941.1 hypothetical protein -
OS089_RS13020 2633440..2634576 + 1137 Protein_2565 SAP domain-containing protein -
OS089_RS13025 2634619..2635102 + 484 Protein_2566 recombinase family protein -
OS089_RS13030 2635263..2635367 + 105 WP_001802298.1 hypothetical protein Toxin
- 2635363..2635542 - 180 - - Antitoxin
OS089_RS13040 2635816..2636907 - 1092 WP_000495695.1 hypothetical protein -
OS089_RS13045 2637173..2638150 - 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
OS089_RS13050 2638152..2638472 - 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS089_RS13055 2638624..2639289 + 666 WP_001024088.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265319 WP_001802298.1 NZ_CP113049:2635263-2635367 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT265319 NZ_CP113049:c2635542-2635363 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References