Detailed information of TA system TA265319

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2635263..2635542
• Replicon: chromosome
• Accession: NZ_CP113049
• Organism: Staphylococcus aureus strain Ahri

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: OS089_RS13030
• Protein ID: WP_001802298.1
• Coordinates: 2635263..2635367 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2635363..2635542 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS089_RS13000	2630657..2631439	+	783	WP_000908190.1	ABC transporter ATP-binding protein	-
OS089_RS13005	2631507..2632364	+	858	WP_000370919.1	HAD family hydrolase	-
OS089_RS13010	2632558..2632772	-	215	Protein_2563	exotoxin	-
OS089_RS13015	2633059..2633151	-	93	WP_031844941.1	hypothetical protein	-
OS089_RS13020	2633440..2634576	+	1137	Protein_2565	SAP domain-containing protein	-
OS089_RS13025	2634619..2635102	+	484	Protein_2566	recombinase family protein	-
OS089_RS13030	2635263..2635367	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2635363..2635542	-	180	-	-	Antitoxin
OS089_RS13040	2635816..2636907	-	1092	WP_000495695.1	hypothetical protein	-
OS089_RS13045	2637173..2638150	-	978	WP_000019732.1	CDF family zinc efflux transporter CzrB	-
OS089_RS13050	2638152..2638472	-	321	WP_000139802.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
OS089_RS13055	2638624..2639289	+	666	WP_001024088.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T265319 WP_001802298.1 NZ_CP113049:2635263-2635367 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT265319 NZ_CP113049:c2635542-2635363 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin