Detailed information of TA system TA265308

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 734926..735110
• Replicon: chromosome
• Accession: NZ_CP113047
• Organism: Staphylococcus aureus strain Sett

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: OS087_RS04000
• Protein ID: WP_072467491.1
• Coordinates: 735003..735110 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	734926..734986 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS087_RS03985	730494..730661	-	168	WP_031866196.1	hypothetical protein	-
OS087_RS03990	730892..732625	-	1734	WP_000486502.1	ABC transporter ATP-binding protein	-
OS087_RS03995	732650..734413	-	1764	WP_001064834.1	ABC transporter ATP-binding protein	-
-	734926..734986	+	61	-	-	Antitoxin
OS087_RS04000	735003..735110	-	108	WP_072467491.1	type I toxin-antitoxin system Fst family toxin	Toxin
OS087_RS04005	735244..735630	-	387	WP_000779348.1	flippase GtxA	-
OS087_RS04010	735887..737029	+	1143	WP_001176873.1	glycerate kinase	-
OS087_RS04015	737089..737748	+	660	WP_000831298.1	membrane protein	-
OS087_RS04020	737930..739141	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
OS087_RS04025	739264..739737	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3944.67 Da
• Isoelectric Point: 10.4934

>T265308 WP_072467491.1 NZ_CP113047:c735110-735003 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 61 bp

>AT265308 NZ_CP113047:734926-734986 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin