265306

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 456586..456783 Replicon chromosome
Accession NZ_CP113047
Organism Staphylococcus aureus strain Sett

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS087_RS02545 Protein ID WP_001802298.1
Coordinates 456679..456783 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 456586..456624 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS087_RS02520 452761..453426 - 666 WP_001024095.1 SDR family oxidoreductase -
OS087_RS02525 453578..453898 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS087_RS02530 453900..454880 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OS087_RS02535 455146..456237 + 1092 WP_000495681.1 hypothetical protein -
OS087_RS02540 456566..456640 + 75 Protein_463 hypothetical protein -
- 456586..456624 + 39 - - Antitoxin
OS087_RS02545 456679..456783 - 105 WP_001802298.1 hypothetical protein Toxin
OS087_RS02550 457463..457621 + 159 WP_001792784.1 hypothetical protein -
OS087_RS02555 458279..459136 - 858 WP_000370928.1 HAD family hydrolase -
OS087_RS02560 459204..459986 - 783 WP_267830498.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265306 WP_001802298.1 NZ_CP113047:c456783-456679 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT265306 NZ_CP113047:456586-456624 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References