Detailed information of TA system TA265297

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 138430..138610
• Replicon: chromosome
• Accession: NZ_CP113047
• Organism: Staphylococcus aureus strain Sett

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS087_RS00610
• Protein ID: WP_001801861.1
• Coordinates: 138430..138525 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	138553..138610 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS087_RS00575	133471..134097	+	627	WP_000669019.1	hypothetical protein	-
OS087_RS00580	134138..134479	+	342	WP_049311638.1	DUF3969 family protein	-
OS087_RS00585	134580..135152	+	573	Protein_116	hypothetical protein	-
OS087_RS00590	135350..135978	-	629	Protein_117	ImmA/IrrE family metallo-endopeptidase	-
OS087_RS00595	136278..136454	-	177	WP_000375476.1	hypothetical protein	-
OS087_RS00600	136465..136848	-	384	WP_000070811.1	hypothetical protein	-
OS087_RS00605	137533..137979	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
OS087_RS00610	138430..138525	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	138553..138610	-	58	-	-	Antitoxin
OS087_RS00615	138648..138749	+	102	WP_001791232.1	hypothetical protein	-
OS087_RS00620	138727..138909	-	183	Protein_123	transposase	-
OS087_RS00625	139097..139471	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
OS087_RS00630	139493..139771	-	279	WP_001798632.1	DUF1433 domain-containing protein	-
OS087_RS00635	140050..140493	-	444	WP_000742594.1	DUF1433 domain-containing protein	-
OS087_RS00640	141141..142259	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	130911..179879	48968

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265297 WP_001801861.1 NZ_CP113047:138430-138525 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT265297 NZ_CP113047:c138610-138553 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin