Detailed information of TA system TA265295

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2809308..2809490
• Replicon: chromosome
• Accession: NZ_CP113044
• Organism: Staphylococcus aureus strain LeBlanc

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS085_RS13985
• Protein ID: WP_001801861.1
• Coordinates: 2809308..2809403 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2809431..2809490 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS085_RS13945	2804968..2805594	+	627	Protein_2740	hypothetical protein	-
OS085_RS13950	2805635..2805979	+	345	WP_000627551.1	DUF3969 family protein	-
OS085_RS13955	2806077..2806628	+	552	WP_000414205.1	hypothetical protein	-
OS085_RS13960	2806846..2807487	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
OS085_RS13965	2807601..2807786	-	186	WP_000809857.1	hypothetical protein	-
OS085_RS13970	2807788..2807964	-	177	WP_000375476.1	hypothetical protein	-
OS085_RS13975	2807975..2808358	-	384	WP_267836538.1	hypothetical protein	-
OS085_RS13980	2808962..2809105	-	144	WP_001549059.1	transposase	-
OS085_RS13985	2809308..2809403	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2809431..2809490	-	60	-	-	Antitoxin
OS085_RS13990	2809526..2809627	+	102	WP_001791893.1	hypothetical protein	-
OS085_RS13995	2809605..2809781	-	177	Protein_2750	transposase	-
OS085_RS14000	2809975..2810352	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2802408..2829406	26998

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265295 WP_001801861.1 NZ_CP113044:2809308-2809403 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT265295 NZ_CP113044:c2809490-2809431 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin