Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2853050..2853232 Replicon chromosome
Accession NZ_CP113042
Organism Staphylococcus aureus strain Seraphine

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OS079_RS14320 Protein ID WP_001801861.1
Coordinates 2853050..2853145 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2853173..2853232 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS079_RS14280 2848710..2849336 + 627 Protein_2807 hypothetical protein -
OS079_RS14285 2849377..2849721 + 345 WP_000627551.1 DUF3969 family protein -
OS079_RS14290 2849819..2850370 + 552 WP_000414205.1 hypothetical protein -
OS079_RS14295 2850588..2851229 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
OS079_RS14300 2851343..2851528 - 186 WP_000809857.1 hypothetical protein -
OS079_RS14305 2851530..2851706 - 177 WP_000375476.1 hypothetical protein -
OS079_RS14310 2851717..2852100 - 384 WP_000070811.1 hypothetical protein -
OS079_RS14315 2852704..2852847 - 144 WP_001549059.1 transposase -
OS079_RS14320 2853050..2853145 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2853173..2853232 - 60 - - Antitoxin
OS079_RS14325 2853268..2853369 + 102 WP_001791893.1 hypothetical protein -
OS079_RS14330 2853347..2853523 - 177 Protein_2817 transposase -
OS079_RS14335 2853717..2854094 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T265283 WP_001801861.1 NZ_CP113042:2853050-2853145 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT265283 NZ_CP113042:c2853232-2853173 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References