Detailed information of TA system TA265283

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2853050..2853232
• Replicon: chromosome
• Accession: NZ_CP113042
• Organism: Staphylococcus aureus strain Seraphine

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS079_RS14320
• Protein ID: WP_001801861.1
• Coordinates: 2853050..2853145 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2853173..2853232 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS079_RS14280	2848710..2849336	+	627	Protein_2807	hypothetical protein	-
OS079_RS14285	2849377..2849721	+	345	WP_000627551.1	DUF3969 family protein	-
OS079_RS14290	2849819..2850370	+	552	WP_000414205.1	hypothetical protein	-
OS079_RS14295	2850588..2851229	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
OS079_RS14300	2851343..2851528	-	186	WP_000809857.1	hypothetical protein	-
OS079_RS14305	2851530..2851706	-	177	WP_000375476.1	hypothetical protein	-
OS079_RS14310	2851717..2852100	-	384	WP_000070811.1	hypothetical protein	-
OS079_RS14315	2852704..2852847	-	144	WP_001549059.1	transposase	-
OS079_RS14320	2853050..2853145	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2853173..2853232	-	60	-	-	Antitoxin
OS079_RS14325	2853268..2853369	+	102	WP_001791893.1	hypothetical protein	-
OS079_RS14330	2853347..2853523	-	177	Protein_2817	transposase	-
OS079_RS14335	2853717..2854094	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265283 WP_001801861.1 NZ_CP113042:2853050-2853145 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT265283 NZ_CP113042:c2853232-2853173 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin