Detailed information of TA system TA265276

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 267178..267457
• Replicon: chromosome
• Accession: NZ_CP113042
• Organism: Staphylococcus aureus strain Seraphine

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: OS079_RS01500
• Protein ID: WP_001802298.1
• Coordinates: 267353..267457 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	267178..267357 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS079_RS01475	263377..264042	-	666	WP_001024094.1	SDR family oxidoreductase	-
OS079_RS01480	264194..264514	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
OS079_RS01485	264516..265496	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
OS079_RS01490	265762..266853	+	1092	WP_000495671.1	lytic regulatory protein	-
-	267178..267357	+	180	-	-	Antitoxin
OS079_RS01500	267353..267457	-	105	WP_001802298.1	hypothetical protein	Toxin
OS079_RS01505	267618..268101	-	484	Protein_290	recombinase family protein	-
OS079_RS01510	268144..269280	-	1137	WP_000115564.1	SAP domain-containing protein	-
OS079_RS01515	269569..269661	+	93	WP_001790138.1	hypothetical protein	-
OS079_RS01520	269950..270134	+	185	Protein_293	exotoxin	-
OS079_RS01525	270366..271223	-	858	WP_000370924.1	HAD family hydrolase	-
OS079_RS01530	271291..272073	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T265276 WP_001802298.1 NZ_CP113042:c267457-267353 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT265276 NZ_CP113042:267178-267357 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin