265265

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 806598..806782 Replicon chromosome
Accession NZ_CP113039
Organism Staphylococcus aureus strain Gwen

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag OS086_RS04355 Protein ID WP_000482652.1
Coordinates 806675..806782 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 806598..806658 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS086_RS04340 802053..802184 - 132 WP_223197975.1 hypothetical protein -
OS086_RS04345 802451..804184 - 1734 WP_000486487.1 ABC transporter ATP-binding protein -
OS086_RS04350 804209..805972 - 1764 WP_001064825.1 ABC transporter ATP-binding protein -
- 806598..806658 + 61 - - Antitoxin
OS086_RS04355 806675..806782 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
OS086_RS04360 806916..807302 - 387 WP_000779360.1 flippase GtxA -
OS086_RS04365 807570..808712 + 1143 WP_001176863.1 glycerate kinase -
OS086_RS04370 808772..809431 + 660 WP_000831298.1 membrane protein -
OS086_RS04375 809613..810824 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OS086_RS04380 810947..811420 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T265265 WP_000482652.1 NZ_CP113039:c806782-806675 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265265 NZ_CP113039:806598-806658 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References