Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 2341607..2342021 | Replicon | chromosome |
Accession | NZ_CP113037 | ||
Organism | Staphylococcus aureus strain Zilean |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | OS091_RS11885 | Protein ID | WP_001065064.1 |
Coordinates | 2341770..2342021 (-) | Length | 84 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | OS091_RS11880 | Protein ID | WP_000028424.1 |
Coordinates | 2341607..2341780 (-) | Length | 58 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OS091_RS11845 | 2338022..2339246 | - | 1225 | Protein_2233 | PBSX family phage terminase large subunit | - |
OS091_RS11850 | 2339239..2339700 | - | 462 | WP_001794914.1 | hypothetical protein | - |
OS091_RS11855 | 2340088..2340489 | - | 402 | WP_000286968.1 | hypothetical protein | - |
OS091_RS11860 | 2340490..2340663 | - | 174 | WP_149569684.1 | transcriptional activator RinB | - |
OS091_RS11865 | 2340660..2340866 | - | 207 | WP_029625633.1 | DUF1381 domain-containing protein | - |
OS091_RS11870 | 2340903..2341430 | - | 528 | WP_149569683.1 | dUTPase | - |
OS091_RS11875 | 2341445..2341606 | - | 162 | WP_000889680.1 | hypothetical protein | - |
OS091_RS11880 | 2341607..2341780 | - | 174 | WP_000028424.1 | hypothetical protein | Antitoxin |
OS091_RS11885 | 2341770..2342021 | - | 252 | WP_001065064.1 | DUF1024 family protein | Toxin |
OS091_RS11890 | 2342036..2342284 | - | 249 | WP_001126846.1 | phi PVL orf 51-like protein | - |
OS091_RS11895 | 2342285..2342656 | - | 372 | WP_001140289.1 | SA1788 family PVL leukocidin-associated protein | - |
OS091_RS11900 | 2342657..2342842 | - | 186 | WP_001187242.1 | DUF3113 family protein | - |
OS091_RS11905 | 2342847..2343251 | - | 405 | WP_000049784.1 | DUF1064 domain-containing protein | - |
OS091_RS11910 | 2343262..2343483 | - | 222 | WP_001123673.1 | DUF3269 family protein | - |
OS091_RS11915 | 2343496..2343657 | - | 162 | WP_000237153.1 | hypothetical protein | - |
OS091_RS11920 | 2343651..2344425 | - | 775 | Protein_2248 | ATP-binding protein | - |
OS091_RS11925 | 2344435..2345205 | - | 771 | WP_031769013.1 | conserved phage C-terminal domain-containing protein | - |
OS091_RS11930 | 2345270..2346127 | + | 858 | WP_000371250.1 | DUF4393 domain-containing protein | - |
OS091_RS11935 | 2346233..2346907 | - | 675 | WP_031769015.1 | putative HNHc nuclease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2313378..2357068 | 43690 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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