Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1030174..1030453 Replicon chromosome
Accession NZ_CP113037
Organism Staphylococcus aureus strain Zilean

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS091_RS05255 Protein ID WP_001802298.1
Coordinates 1030174..1030278 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1030274..1030453 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS091_RS05225 1025568..1026350 + 783 WP_000908190.1 ABC transporter ATP-binding protein -
OS091_RS05230 1026418..1027275 + 858 WP_000370919.1 HAD family hydrolase -
OS091_RS05235 1027469..1027683 - 215 Protein_960 exotoxin -
OS091_RS05240 1027970..1028062 - 93 WP_031844941.1 hypothetical protein -
OS091_RS05245 1028351..1029487 + 1137 Protein_962 SAP domain-containing protein -
OS091_RS05250 1029530..1030013 + 484 Protein_963 recombinase family protein -
OS091_RS05255 1030174..1030278 + 105 WP_001802298.1 hypothetical protein Toxin
- 1030274..1030453 - 180 - - Antitoxin
OS091_RS05265 1030727..1031818 - 1092 WP_267842140.1 transcriptional regulator -
OS091_RS05270 1032084..1033061 - 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
OS091_RS05275 1033063..1033383 - 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS091_RS05280 1033535..1034200 + 666 WP_001024088.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265245 WP_001802298.1 NZ_CP113037:1030174-1030278 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT265245 NZ_CP113037:c1030453-1030274 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References