Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 768594..769111 | Replicon | chromosome |
Accession | NZ_CP113037 | ||
Organism | Staphylococcus aureus strain Zilean |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A2S6D1N9 |
Locus tag | OS091_RS03905 | Protein ID | WP_000113263.1 |
Coordinates | 768845..769111 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | T1YB60 |
Locus tag | OS091_RS03900 | Protein ID | WP_000584499.1 |
Coordinates | 768594..768845 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OS091_RS03870 | 764294..765013 | + | 720 | WP_000479576.1 | amino acid ABC transporter permease | - |
OS091_RS03875 | 765010..765741 | + | 732 | WP_149569703.1 | amino acid ABC transporter ATP-binding protein | - |
OS091_RS03880 | 765838..767088 | - | 1251 | WP_001012236.1 | FemA/FemB family glycyltransferase FmhA | - |
OS091_RS03885 | 767343..767705 | + | 363 | WP_000819839.1 | DUF4467 domain-containing protein | - |
OS091_RS03890 | 767724..768323 | + | 600 | WP_000162810.1 | DsbA family protein | - |
OS091_RS03895 | 768330..768421 | + | 92 | Protein_701 | hypothetical protein | - |
OS091_RS03900 | 768594..768845 | + | 252 | WP_000584499.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
OS091_RS03905 | 768845..769111 | + | 267 | WP_000113263.1 | Txe/YoeB family addiction module toxin | Toxin |
OS091_RS03910 | 769146..769217 | + | 72 | WP_223200558.1 | hypothetical protein | - |
OS091_RS03915 | 769405..770952 | + | 1548 | WP_000727757.1 | zinc ABC transporter substrate-binding lipoprotein AdcA | - |
OS091_RS03920 | 771138..771605 | + | 468 | WP_000153338.1 | SRPBCC domain-containing protein | - |
OS091_RS03925 | 771692..771874 | + | 183 | WP_000079140.1 | hypothetical protein | - |
OS091_RS03930 | 772078..772902 | + | 825 | WP_000594633.1 | formate/nitrite transporter family protein | - |
OS091_RS03935 | 773315..773851 | + | 537 | WP_000185901.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2S6D1N9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | T1YB60 |