Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 743656..743840 Replicon chromosome
Accession NZ_CP113037
Organism Staphylococcus aureus strain Zilean

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OS091_RS03770 Protein ID WP_000482647.1
Coordinates 743656..743763 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 743780..743840 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS091_RS03745 739018..739491 + 474 WP_000456483.1 GyrI-like domain-containing protein -
OS091_RS03750 739614..740825 - 1212 WP_001191921.1 multidrug effflux MFS transporter -
OS091_RS03755 741008..741667 - 660 WP_000831298.1 membrane protein -
OS091_RS03760 741727..742869 - 1143 WP_001176863.1 glycerate kinase -
OS091_RS03765 743137..743523 + 387 WP_000779353.1 flippase GtxA -
OS091_RS03770 743656..743763 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 743780..743840 - 61 - - Antitoxin
OS091_RS03775 744411..746123 + 1713 WP_001064821.1 ABC transporter ATP-binding protein -
OS091_RS03780 746199..747932 + 1734 WP_000488493.1 ABC transporter ATP-binding protein -
OS091_RS03785 748163..748330 + 168 WP_031845053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T265242 WP_000482647.1 NZ_CP113037:743656-743763 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265242 NZ_CP113037:c743840-743780 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References