265239

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2606892..2607076 Replicon chromosome
Accession NZ_CP113032
Organism Staphylococcus aureus strain Akali

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag OS080_RS13635 Protein ID WP_000482650.1
Coordinates 2606969..2607076 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2606892..2606952 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS080_RS13620 2602422..2602589 - 168 WP_001790576.1 hypothetical protein -
OS080_RS13625 2602820..2604553 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OS080_RS13630 2604578..2606341 - 1764 WP_023180203.1 ABC transporter ATP-binding protein -
- 2606892..2606952 + 61 - - Antitoxin
OS080_RS13635 2606969..2607076 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
OS080_RS13640 2607210..2607596 - 387 WP_000779358.1 flippase GtxA -
OS080_RS13645 2607864..2609006 + 1143 WP_001176863.1 glycerate kinase -
OS080_RS13650 2609066..2609725 + 660 WP_000831298.1 membrane protein -
OS080_RS13655 2609907..2611118 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OS080_RS13660 2611241..2611714 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T265239 WP_000482650.1 NZ_CP113032:c2607076-2606969 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265239 NZ_CP113032:2606892-2606952 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References