Detailed information of TA system TA265235

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2316566..2316845
• Replicon: chromosome
• Accession: NZ_CP113032
• Organism: Staphylococcus aureus strain Akali

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: OS080_RS12110
• Protein ID: WP_001802298.1
• Coordinates: 2316741..2316845 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2316566..2316745 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS080_RS12085	2312765..2313430	-	666	WP_001024094.1	SDR family oxidoreductase	-
OS080_RS12090	2313582..2313902	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
OS080_RS12095	2313904..2314884	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
OS080_RS12100	2315150..2316241	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2316566..2316745	+	180	-	-	Antitoxin
OS080_RS12110	2316741..2316845	-	105	WP_001802298.1	hypothetical protein	Toxin
OS080_RS12115	2317006..2317489	-	484	Protein_2325	recombinase family protein	-
OS080_RS12120	2317532..2318668	-	1137	WP_000115564.1	SAP domain-containing protein	-
OS080_RS12125	2318957..2319049	+	93	WP_001790138.1	hypothetical protein	-
OS080_RS12130	2319338..2319522	+	185	Protein_2328	exotoxin	-
OS080_RS12135	2319754..2320611	-	858	WP_000370924.1	HAD family hydrolase	-
OS080_RS12140	2320679..2321461	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T265235 WP_001802298.1 NZ_CP113032:c2316845-2316741 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT265235 NZ_CP113032:2316566-2316745 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin