Detailed information of TA system TA265227

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1909595..1909777
• Replicon: chromosome
• Accession: NZ_CP113032
• Organism: Staphylococcus aureus strain Akali

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS080_RS09585
• Protein ID: WP_001801861.1
• Coordinates: 1909595..1909690 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1909718..1909777 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS080_RS09545	1905255..1905881	+	627	WP_000669046.1	hypothetical protein	-
OS080_RS09550	1905922..1906266	+	345	WP_000627551.1	DUF3969 family protein	-
OS080_RS09555	1906364..1906915	+	552	WP_267793679.1	hypothetical protein	-
OS080_RS09560	1907133..1907774	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
OS080_RS09565	1907888..1908073	-	186	WP_000809857.1	hypothetical protein	-
OS080_RS09570	1908075..1908251	-	177	WP_000375476.1	hypothetical protein	-
OS080_RS09575	1908262..1908645	-	384	WP_000070811.1	hypothetical protein	-
OS080_RS09580	1909249..1909392	-	144	WP_001549059.1	transposase	-
OS080_RS09585	1909595..1909690	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1909718..1909777	-	60	-	-	Antitoxin
OS080_RS09590	1909813..1909914	+	102	WP_001791893.1	hypothetical protein	-
OS080_RS09595	1909892..1910068	-	177	Protein_1866	transposase	-
OS080_RS09600	1910262..1910639	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1902695..1927949	25254

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265227 WP_001801861.1 NZ_CP113032:1909595-1909690 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT265227 NZ_CP113032:c1909777-1909718 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin