Detailed information of TA system TA265221

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1460904..1461086
• Replicon: chromosome
• Accession: NZ_CP113029
• Organism: Staphylococcus aureus strain Zoe

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS075_RS07645
• Protein ID: WP_001801861.1
• Coordinates: 1460991..1461086 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1460904..1460963 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS075_RS07630	1460042..1460419	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
OS075_RS07635	1460613..1460789	+	177	Protein_1433	transposase	-
OS075_RS07640	1460767..1460868	-	102	WP_001791893.1	hypothetical protein	-
-	1460904..1460963	+	60	-	-	Antitoxin
OS075_RS07645	1460991..1461086	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
OS075_RS07650	1461289..1461432	+	144	WP_001549059.1	transposase	-
OS075_RS07655	1462036..1462419	+	384	WP_000070811.1	hypothetical protein	-
OS075_RS07660	1462430..1462606	+	177	WP_000375476.1	hypothetical protein	-
OS075_RS07665	1462608..1462793	+	186	WP_000809857.1	hypothetical protein	-
OS075_RS07670	1462907..1463548	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
OS075_RS07675	1463766..1464317	-	552	WP_000414205.1	hypothetical protein	-
OS075_RS07680	1464415..1464759	-	345	WP_000627551.1	DUF3969 family protein	-
OS075_RS07685	1464800..1465426	-	627	Protein_1443	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265221 WP_001801861.1 NZ_CP113029:c1461086-1460991 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT265221 NZ_CP113029:1460904-1460963 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin