Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1125212..1125475 Replicon chromosome
Accession NZ_CP113029
Organism Staphylococcus aureus strain Zoe

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS075_RS05670 Protein ID WP_001802298.1
Coordinates 1125212..1125316 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1125311..1125475 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS075_RS05640 (1120596) 1120596..1121378 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
OS075_RS05645 (1121446) 1121446..1122303 + 858 WP_000370924.1 HAD family hydrolase -
OS075_RS05650 (1122535) 1122535..1122719 - 185 Protein_1080 exotoxin -
OS075_RS05655 (1123008) 1123008..1123100 - 93 WP_001790138.1 hypothetical protein -
OS075_RS05660 (1123389) 1123389..1124525 + 1137 WP_000115564.1 SAP domain-containing protein -
OS075_RS05665 (1124568) 1124568..1125051 + 484 Protein_1083 recombinase family protein -
OS075_RS05670 (1125212) 1125212..1125316 + 105 WP_001802298.1 hypothetical protein Toxin
- 1125311..1125475 - 165 - - Antitoxin
OS075_RS05680 (1125816) 1125816..1126907 - 1092 WP_000495671.1 lytic regulatory protein -
OS075_RS05685 (1127173) 1127173..1128153 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
OS075_RS05690 (1128155) 1128155..1128475 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS075_RS05695 (1128627) 1128627..1129292 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265212 WP_001802298.1 NZ_CP113029:1125212-1125316 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT265212 NZ_CP113029:c1125475-1125311 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References