Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF1/-
Location 1557021..1557359 Replicon chromosome
Accession NZ_CP113027
Organism Staphylococcus aureus strain Syndra

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag OS083_RS08395 Protein ID WP_011447039.1
Coordinates 1557021..1557197 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1557185..1557359 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS083_RS08375 1554708..1554860 + 153 WP_000654329.1 hypothetical protein -
OS083_RS08380 1554907..1555194 + 288 WP_001040255.1 hypothetical protein -
OS083_RS08385 1555250..1555624 + 375 WP_000340977.1 hypothetical protein -
OS083_RS08390 1556045..1556818 + 774 WP_025174055.1 staphylococcal enterotoxin type P -
OS083_RS08395 1557021..1557197 + 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 1557185..1557359 - 175 - - Antitoxin
OS083_RS08405 1557409..1557663 + 255 WP_000611512.1 phage holin -
OS083_RS08410 1557675..1558430 + 756 WP_000861038.1 CHAP domain-containing protein -
OS083_RS08415 1558621..1559112 + 492 WP_000920038.1 staphylokinase -
OS083_RS08420 1559763..1560098 + 336 Protein_1539 SH3 domain-containing protein -
OS083_RS08425 1560609..1560959 + 351 WP_000702263.1 complement inhibitor SCIN-A -
OS083_RS08430 1561012..1561272 - 261 WP_001791826.1 hypothetical protein -
OS083_RS08435 1561583..1561762 - 180 WP_000669791.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - see / sak / scn 1470412..1563829 93417


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T265204 WP_011447039.1 NZ_CP113027:1557021-1557197 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 175 bp

>AT265204 NZ_CP113027:c1557359-1557185 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References