Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 881113..881297 Replicon chromosome
Accession NZ_CP113027
Organism Staphylococcus aureus strain Syndra

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OS083_RS04475 Protein ID WP_000482647.1
Coordinates 881113..881220 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 881237..881297 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS083_RS04450 876475..876948 + 474 WP_000456483.1 GyrI-like domain-containing protein -
OS083_RS04455 877071..878282 - 1212 WP_001191921.1 multidrug effflux MFS transporter -
OS083_RS04460 878465..879124 - 660 WP_000831298.1 membrane protein -
OS083_RS04465 879184..880326 - 1143 WP_001176863.1 glycerate kinase -
OS083_RS04470 880594..880980 + 387 WP_000779353.1 flippase GtxA -
OS083_RS04475 881113..881220 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 881237..881297 - 61 - - Antitoxin
OS083_RS04480 881868..883580 + 1713 WP_001064821.1 ABC transporter ATP-binding protein -
OS083_RS04485 883656..885389 + 1734 WP_000488493.1 ABC transporter ATP-binding protein -
OS083_RS04490 885620..885787 + 168 WP_031845053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T265192 WP_000482647.1 NZ_CP113027:881113-881220 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265192 NZ_CP113027:c881297-881237 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References