Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1430898..1431080 Replicon chromosome
Accession NZ_CP113018
Organism Staphylococcus aureus strain Taliyah

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OS090_RS07665 Protein ID WP_001801861.1
Coordinates 1430985..1431080 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1430898..1430957 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS090_RS07650 1430036..1430413 + 378 WP_001037045.1 DUF1433 domain-containing protein -
OS090_RS07655 1430607..1430783 + 177 Protein_1438 transposase -
OS090_RS07660 1430761..1430862 - 102 WP_001791893.1 hypothetical protein -
- 1430898..1430957 + 60 - - Antitoxin
OS090_RS07665 1430985..1431080 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
OS090_RS07670 1431283..1431426 + 144 WP_001549059.1 transposase -
OS090_RS07675 1432030..1432413 + 384 WP_000070811.1 hypothetical protein -
OS090_RS07680 1432424..1432600 + 177 WP_000375476.1 hypothetical protein -
OS090_RS07685 1432602..1432787 + 186 WP_000809857.1 hypothetical protein -
OS090_RS07690 1432901..1433542 + 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
OS090_RS07695 1433760..1434311 - 552 WP_267793679.1 hypothetical protein -
OS090_RS07700 1434409..1434753 - 345 WP_000627551.1 DUF3969 family protein -
OS090_RS07705 1434794..1435420 - 627 WP_000669046.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T265188 WP_001801861.1 NZ_CP113018:c1431080-1430985 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp


Antitoxin


Download         Length: 60 bp

>AT265188 NZ_CP113018:1430898-1430957 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References