Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1025164..1025427 Replicon chromosome
Accession NZ_CP113018
Organism Staphylococcus aureus strain Taliyah

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS090_RS05150 Protein ID WP_001802298.1
Coordinates 1025164..1025268 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1025263..1025427 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS090_RS05120 1020548..1021330 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
OS090_RS05125 1021398..1022255 + 858 WP_000370924.1 HAD family hydrolase -
OS090_RS05130 1022487..1022671 - 185 Protein_978 exotoxin -
OS090_RS05135 1022960..1023052 - 93 WP_001790138.1 hypothetical protein -
OS090_RS05140 1023341..1024477 + 1137 WP_000115564.1 SAP domain-containing protein -
OS090_RS05145 1024520..1025003 + 484 Protein_981 recombinase family protein -
OS090_RS05150 1025164..1025268 + 105 WP_001802298.1 hypothetical protein Toxin
- 1025263..1025427 - 165 - - Antitoxin
OS090_RS05160 1025768..1026859 - 1092 WP_000495671.1 lytic regulatory protein -
OS090_RS05165 1027125..1028105 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
OS090_RS05170 1028107..1028427 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS090_RS05175 1028579..1029244 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265178 WP_001802298.1 NZ_CP113018:1025164-1025268 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT265178 NZ_CP113018:c1025427-1025263 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References