Detailed information of TA system TA265173

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2812732..2812912
• Replicon: chromosome
• Accession: NZ_CP113016
• Organism: Staphylococcus aureus strain Azir

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OS077_RS14050
• Protein ID: WP_001801861.1
• Coordinates: 2812732..2812827 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2812855..2812912 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS077_RS14015	2807894..2808889	+	996	WP_000070649.1	DUF4352 domain-containing protein	-
OS077_RS14020	2808963..2809589	+	627	WP_000669028.1	hypothetical protein	-
OS077_RS14025	2809676..2810183	+	508	Protein_2756	hypothetical protein	-
OS077_RS14030	2810210..2810962	+	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
OS077_RS14035	2811094..2811720	-	627	Protein_2758	ImmA/IrrE family metallo-endopeptidase	-
OS077_RS14040	2811834..2812280	-	447	WP_000747805.1	DUF1433 domain-containing protein	-
OS077_RS14045	2812456..2812587	-	132	WP_001808010.1	hypothetical protein	-
OS077_RS14050	2812732..2812827	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2812855..2812912	-	58	-	-	Antitoxin
OS077_RS14055	2812950..2813048	+	99	Protein_2762	hypothetical protein	-
OS077_RS14060	2813478..2814602	-	1125	WP_223876714.1	hypothetical protein	-
OS077_RS14065	2814664..2815173	-	510	WP_224684909.1	hypothetical protein	-
OS077_RS14070	2815433..2816605	+	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
OS077_RS14075	2816657..2817097	-	441	Protein_2766	staphylococcal enterotoxin type U	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	selk	2811450..2820376	8926

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T265173 WP_001801861.1 NZ_CP113016:2812732-2812827 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT265173 NZ_CP113016:c2812912-2812855 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin