Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 517997..518181 Replicon chromosome
Accession NZ_CP113016
Organism Staphylococcus aureus strain Azir

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OS077_RS02695 Protein ID WP_000482647.1
Coordinates 518074..518181 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 517997..518057 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS077_RS02680 513527..513694 - 168 WP_001790576.1 hypothetical protein -
OS077_RS02685 513925..515658 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OS077_RS02690 515683..517446 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 517997..518057 + 61 - - Antitoxin
OS077_RS02695 518074..518181 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OS077_RS02700 518315..518701 - 387 WP_000779360.1 flippase GtxA -
OS077_RS02705 518959..520101 + 1143 WP_001176863.1 glycerate kinase -
OS077_RS02710 520161..520820 + 660 WP_000831298.1 membrane protein -
OS077_RS02715 521002..522213 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OS077_RS02720 522336..522809 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T265168 WP_000482647.1 NZ_CP113016:c518181-518074 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265168 NZ_CP113016:517997-518057 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References