Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 233199..233396 Replicon chromosome
Accession NZ_CP113016
Organism Staphylococcus aureus strain Azir

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS077_RS01205 Protein ID WP_001802298.1
Coordinates 233292..233396 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 233199..233237 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS077_RS01180 229374..230039 - 666 WP_001024095.1 SDR family oxidoreductase -
OS077_RS01185 230191..230511 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS077_RS01190 230513..231493 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OS077_RS01195 231759..232850 + 1092 WP_000495681.1 hypothetical protein -
OS077_RS01200 233179..233253 + 75 Protein_229 hypothetical protein -
- 233199..233237 + 39 - - Antitoxin
OS077_RS01205 233292..233396 - 105 WP_001802298.1 hypothetical protein Toxin
OS077_RS01210 234076..234234 + 159 WP_001792784.1 hypothetical protein -
OS077_RS01215 234892..235749 - 858 WP_000370930.1 HAD family hydrolase -
OS077_RS01220 235817..236599 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265166 WP_001802298.1 NZ_CP113016:c233396-233292 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT265166 NZ_CP113016:233199-233237 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References