Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 3021752..3022015 Replicon chromosome
Accession NZ_CP113015
Organism Staphylococcus aureus strain Zed

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OS078_RS15645 Protein ID WP_001802298.1
Coordinates 3021911..3022015 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 3021752..3021916 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS078_RS15620 3017935..3018600 - 666 WP_001024094.1 SDR family oxidoreductase -
OS078_RS15625 3018752..3019072 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OS078_RS15630 3019074..3020054 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
OS078_RS15635 3020320..3021411 + 1092 WP_000495671.1 lytic regulatory protein -
- 3021752..3021916 + 165 - - Antitoxin
OS078_RS15645 3021911..3022015 - 105 WP_001802298.1 hypothetical protein Toxin
OS078_RS15650 3022176..3022659 - 484 Protein_3017 recombinase family protein -
OS078_RS15655 3022702..3023838 - 1137 WP_000115564.1 SAP domain-containing protein -
OS078_RS15660 3024127..3024219 + 93 WP_001790138.1 hypothetical protein -
OS078_RS15665 3024508..3024692 + 185 Protein_3020 exotoxin -
OS078_RS15670 3024924..3025781 - 858 WP_000370924.1 HAD family hydrolase -
OS078_RS15675 3025849..3026631 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T265162 WP_001802298.1 NZ_CP113015:c3022015-3021911 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT265162 NZ_CP113015:3021752-3021916 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References