Detailed information of TA system TA265161

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 3021736..3022015
• Replicon: chromosome
• Accession: NZ_CP113015
• Organism: Staphylococcus aureus strain Zed

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: OS078_RS15645
• Protein ID: WP_001802298.1
• Coordinates: 3021911..3022015 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	3021736..3021915 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS078_RS15620	3017935..3018600	-	666	WP_001024094.1	SDR family oxidoreductase	-
OS078_RS15625	3018752..3019072	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
OS078_RS15630	3019074..3020054	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
OS078_RS15635	3020320..3021411	+	1092	WP_000495671.1	lytic regulatory protein	-
-	3021736..3021915	+	180	-	-	Antitoxin
OS078_RS15645	3021911..3022015	-	105	WP_001802298.1	hypothetical protein	Toxin
OS078_RS15650	3022176..3022659	-	484	Protein_3017	recombinase family protein	-
OS078_RS15655	3022702..3023838	-	1137	WP_000115564.1	SAP domain-containing protein	-
OS078_RS15660	3024127..3024219	+	93	WP_001790138.1	hypothetical protein	-
OS078_RS15665	3024508..3024692	+	185	Protein_3020	exotoxin	-
OS078_RS15670	3024924..3025781	-	858	WP_000370924.1	HAD family hydrolase	-
OS078_RS15675	3025849..3026631	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T265161 WP_001802298.1 NZ_CP113015:c3022015-3021911 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT265161 NZ_CP113015:3021736-3021915 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin