Detailed information of TA system TA265155

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF3/-
• Location: 2773462..2773761
• Replicon: chromosome
• Accession: NZ_CP113015
• Organism: Staphylococcus aureus strain Zed

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: A0A4U0AGH1
• Locus tag: OS078_RS14095
• Protein ID: WP_072482930.1
• Coordinates: 2773585..2773761 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2773462..2773517 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS078_RS14055	2769020..2769199	+	180	WP_000669789.1	hypothetical protein	-
OS078_RS14060	2769510..2769770	+	261	WP_001791826.1	hypothetical protein	-
OS078_RS14065	2769823..2770173	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
OS078_RS14070	2770683..2771018	-	336	Protein_2706	SH3 domain-containing protein	-
OS078_RS14075	2771670..2772161	-	492	WP_000920041.1	staphylokinase	-
OS078_RS14080	2772352..2773107	-	756	WP_000861038.1	CHAP domain-containing protein	-
OS078_RS14085	2773119..2773373	-	255	WP_000611512.1	phage holin	-
OS078_RS14090	2773425..2773532	+	108	Protein_2710	hypothetical protein	-
-	2773454..2773593	+	140	NuclAT_0	-	-
-	2773454..2773593	+	140	NuclAT_0	-	-
-	2773454..2773593	+	140	NuclAT_0	-	-
-	2773454..2773593	+	140	NuclAT_0	-	-
-	2773462..2773517	+	56	-	-	Antitoxin
OS078_RS14095	2773585..2773761	-	177	WP_072482930.1	type I toxin-antitoxin system toxin PepG1	Toxin
OS078_RS14100	2773870..2774643	-	774	WP_000750412.1	staphylococcal enterotoxin type A	-
OS078_RS14105	2775016..2775390	-	375	WP_000340977.1	hypothetical protein	-
OS078_RS14110	2775446..2775733	-	288	WP_001262621.1	hypothetical protein	-
OS078_RS14115	2775779..2775931	-	153	WP_001000059.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / sea / hlb / groEL	2769823..2827349	57526

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6883.46 Da
• Isoelectric Point: 10.6777

>T265155 WP_072482930.1 NZ_CP113015:c2773761-2773585 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIAFIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 56 bp

>AT265155 NZ_CP113015:2773462-2773517 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A4U0AGH1

Antitoxin