Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2269852..2270036 Replicon chromosome
Accession NZ_CP113009
Organism Staphylococcus aureus strain Orianna

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag OS092_RS11835 Protein ID WP_000482650.1
Coordinates 2269929..2270036 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2269852..2269912 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS092_RS11820 2265382..2265549 - 168 WP_001790576.1 hypothetical protein -
OS092_RS11825 2265780..2267513 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OS092_RS11830 2267538..2269301 - 1764 WP_267835035.1 ABC transporter ATP-binding protein -
- 2269852..2269912 + 61 - - Antitoxin
OS092_RS11835 2269929..2270036 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
OS092_RS11840 2270170..2270556 - 387 WP_000779358.1 flippase GtxA -
OS092_RS11845 2270824..2271966 + 1143 WP_001176863.1 glycerate kinase -
OS092_RS11850 2272026..2272685 + 660 WP_000831298.1 membrane protein -
OS092_RS11855 2272867..2274078 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OS092_RS11860 2274201..2274674 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T265145 WP_000482650.1 NZ_CP113009:c2270036-2269929 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265145 NZ_CP113009:2269852-2269912 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References