Detailed information of TA system TA265102

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF3/-
• Location: 1559996..1560295
• Replicon: chromosome
• Accession: NZ_CP113005
• Organism: Staphylococcus aureus strain Galio

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: A0A4U0AGH1
• Locus tag: OS073_RS08100
• Protein ID: WP_072482930.1
• Coordinates: 1560119..1560295 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1559996..1560051 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OS073_RS08060	1555554..1555733	+	180	WP_000669789.1	hypothetical protein	-
OS073_RS08065	1556044..1556304	+	261	WP_001791826.1	hypothetical protein	-
OS073_RS08070	1556357..1556707	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
OS073_RS08075	1557217..1557552	-	336	Protein_1505	SH3 domain-containing protein	-
OS073_RS08080	1558204..1558695	-	492	WP_000920041.1	staphylokinase	-
OS073_RS08085	1558886..1559641	-	756	WP_000861038.1	CHAP domain-containing protein	-
OS073_RS08090	1559653..1559907	-	255	WP_000611512.1	phage holin	-
OS073_RS08095	1559959..1560066	+	108	Protein_1509	hypothetical protein	-
-	1559988..1560127	+	140	NuclAT_0	-	-
-	1559988..1560127	+	140	NuclAT_0	-	-
-	1559988..1560127	+	140	NuclAT_0	-	-
-	1559988..1560127	+	140	NuclAT_0	-	-
-	1559996..1560051	+	56	-	-	Antitoxin
OS073_RS08100	1560119..1560295	-	177	WP_072482930.1	type I toxin-antitoxin system toxin PepG1	Toxin
OS073_RS08105	1560404..1561177	-	774	WP_000750412.1	staphylococcal enterotoxin type A	-
OS073_RS08110	1561550..1561924	-	375	WP_000340977.1	hypothetical protein	-
OS073_RS08115	1561980..1562267	-	288	WP_001262621.1	hypothetical protein	-
OS073_RS08120	1562313..1562465	-	153	WP_001000059.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / sea / hlb / groEL	1556357..1613883	57526

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6883.46 Da
• Isoelectric Point: 10.6777

>T265102 WP_072482930.1 NZ_CP113005:c1560295-1560119 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIAFIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 56 bp

>AT265102 NZ_CP113005:1559996-1560051 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A4U0AGH1

Antitoxin