Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2071692..2071938 Replicon chromosome
Accession NZ_CP112873
Organism Bacillus subtilis strain O4

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag ORF34_RS10390 Protein ID WP_109789044.1
Coordinates 2071692..2071784 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2071765..2071938 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ORF34_RS10375 2066851..2067186 + 336 WP_009967409.1 hypothetical protein -
ORF34_RS10380 2067233..2070838 - 3606 WP_004399367.1 P-loop NTPase fold protein -
ORF34_RS10385 2071071..2071403 - 333 WP_026009814.1 hypothetical protein -
ORF34_RS10390 2071692..2071784 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2071765..2071938 - 174 - - Antitoxin
ORF34_RS10395 2072053..2072895 - 843 WP_003231327.1 hypothetical protein -
ORF34_RS10400 2073095..2073553 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
ORF34_RS10405 2073563..2075365 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
ORF34_RS10410 2075467..2076024 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2057677..2081355 23678


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-24)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T264901 WP_109789044.1 NZ_CP112873:2071692-2071784 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

Antitoxin


Download         Length: 174 bp

>AT264901 NZ_CP112873:c2071938-2071765 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References