Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1827022..1827626 Replicon chromosome
Accession NZ_CP112868
Organism Pseudomonas quebecensis isolate S1Bt3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OSC49_RS08325 Protein ID WP_266248415.1
Coordinates 1827312..1827626 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OSC49_RS08320 Protein ID WP_181081085.1
Coordinates 1827022..1827309 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSC49_RS08305 (OSC49_08305) 1823693..1825192 + 1500 WP_266249693.1 IS21 family transposase -
OSC49_RS08310 (OSC49_08310) 1825185..1825988 + 804 WP_266248411.1 IS21-like element helper ATPase IstB -
OSC49_RS08315 (OSC49_08315) 1826422..1826859 + 438 WP_266248413.1 hypothetical protein -
OSC49_RS08320 (OSC49_08320) 1827022..1827309 - 288 WP_181081085.1 NadS family protein Antitoxin
OSC49_RS08325 (OSC49_08325) 1827312..1827626 - 315 WP_266248415.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OSC49_RS08330 (OSC49_08330) 1827976..1828113 + 138 Protein_1640 HNH endonuclease -
OSC49_RS08335 (OSC49_08335) 1828207..1828707 + 501 WP_266248417.1 hypothetical protein -
OSC49_RS08340 (OSC49_08340) 1828811..1830307 - 1497 WP_266248419.1 hypothetical protein -
OSC49_RS08345 (OSC49_08345) 1830356..1832275 - 1920 WP_181081080.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1819115..1827626 8511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(42-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-72)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11816.69 Da        Isoelectric Point: 10.2638

>T264896 WP_266248415.1 NZ_CP112868:c1827626-1827312 [Pseudomonas quebecensis]
MIFIETPTFTRRVKELIDDDAYTVFQRALMLNPSAGDVIEGTGGIRKARIAAKGHGKQGGARVIYYHFVSMSQIIRLMIY
PKNEQHALTSDERKALKAAIEHWR

Download         Length: 315 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10635.23 Da        Isoelectric Point: 8.8075

>AT264896 WP_181081085.1 NZ_CP112868:c1827309-1827022 [Pseudomonas quebecensis]
MSKFFDELMGSVQEMNEILRGERQPSREFHVDALQVKEIRKATGLTQAKFAALIDVQLGTLRNWEQGRREPTGPAKALLK
AIHNDPVHVLNALAG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References