Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2424443..2425097 Replicon chromosome
Accession NZ_CP111114
Organism Pseudomonas koreensis strain FP1691

Toxin (Protein)


Gene name higB Uniprot ID A0A854X939
Locus tag OPS05_RS10690 Protein ID WP_027614658.1
Coordinates 2424747..2425097 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OPS05_RS10685 Protein ID WP_027614657.1
Coordinates 2424443..2424757 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPS05_RS10665 (OPS05_10665) 2420862..2421062 + 201 WP_134785998.1 co-regulatory protein PtrA N-terminal domain-containing protein -
OPS05_RS10670 (OPS05_10670) 2421129..2421461 + 333 WP_134785999.1 DUF2790 domain-containing protein -
OPS05_RS10675 (OPS05_10675) 2421580..2422764 - 1185 WP_134786000.1 acyltransferase -
OPS05_RS10680 (OPS05_10680) 2422944..2424269 - 1326 WP_134786001.1 OprD family porin -
OPS05_RS10685 (OPS05_10685) 2424443..2424757 - 315 WP_027614657.1 transcriptional regulator Antitoxin
OPS05_RS10690 (OPS05_10690) 2424747..2425097 - 351 WP_027614658.1 toxin Toxin
OPS05_RS10695 (OPS05_10695) 2425467..2425931 + 465 WP_098968147.1 GNAT family N-acetyltransferase -
OPS05_RS10700 (OPS05_10700) 2426123..2427586 - 1464 WP_003223784.1 NADH-quinone oxidoreductase subunit NuoN -
OPS05_RS10705 (OPS05_10705) 2427594..2429126 - 1533 WP_003223785.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13966.76 Da        Isoelectric Point: 7.2031

>T264854 WP_027614658.1 NZ_CP111114:c2425097-2424747 [Pseudomonas koreensis]
MDALFIELPVFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEDTGGLRKIRFSDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVFNKNEQDDLTPAQKKLFRKTLDRELNARSHYET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11950.86 Da        Isoelectric Point: 9.9896

>AT264854 WP_027614657.1 NZ_CP111114:c2424757-2424443 [Pseudomonas koreensis]
MKRDIFSELMDGLEALADERQGKITLRTHKVQLPKLMPITAEEVIAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A854X939

Antitoxin

Source ID Structure

References