Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 2839048..2839748 | Replicon | chromosome |
| Accession | NZ_CP111110 | ||
| Organism | Pseudomonas chengduensis strain BC1815 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | - |
| Locus tag | OF113_RS13290 | Protein ID | WP_017676846.1 |
| Coordinates | 2839452..2839748 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | A0A1H2LFQ3 |
| Locus tag | OF113_RS13285 | Protein ID | WP_031306592.1 |
| Coordinates | 2839048..2839449 (-) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OF113_RS13265 (OF113_13265) | 2834489..2835847 | - | 1359 | WP_064496017.1 | glutathione-disulfide reductase | - |
| OF113_RS13270 (OF113_13270) | 2835920..2836342 | + | 423 | WP_266206469.1 | VOC family protein | - |
| OF113_RS13275 (OF113_13275) | 2836496..2837335 | - | 840 | WP_003460169.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| OF113_RS13280 (OF113_13280) | 2837378..2838739 | - | 1362 | WP_064496018.1 | UDP-glucose/GDP-mannose dehydrogenase family protein | - |
| OF113_RS13285 (OF113_13285) | 2839048..2839449 | - | 402 | WP_031306592.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| OF113_RS13290 (OF113_13290) | 2839452..2839748 | - | 297 | WP_017676846.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| OF113_RS13295 (OF113_13295) | 2839826..2840167 | + | 342 | WP_139204289.1 | hypothetical protein | - |
| OF113_RS13300 (OF113_13300) | 2840201..2840407 | - | 207 | WP_064496019.1 | hypothetical protein | - |
| OF113_RS13305 (OF113_13305) | 2840664..2840885 | + | 222 | WP_064496020.1 | hypothetical protein | - |
| OF113_RS13310 (OF113_13310) | 2840983..2841771 | + | 789 | WP_266206470.1 | CHAD domain-containing protein | - |
| OF113_RS13315 (OF113_13315) | 2842574..2843344 | - | 771 | WP_090336824.1 | hypothetical protein | - |
| OF113_RS13320 (OF113_13320) | 2843375..2844253 | - | 879 | WP_139204237.1 | hypothetical protein | - |
| OF113_RS13325 (OF113_13325) | 2844326..2844595 | - | 270 | WP_090336826.1 | DNA-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11402.19 Da Isoelectric Point: 7.2011
>T264844 WP_017676846.1 NZ_CP111110:c2839748-2839452 [Pseudomonas chengduensis]
MEKRKPHFKLELVKQAVTEQRYRFTRVALEGGAELGMEMADMLAVISALSSRDFFKSMTTYADHTTWQDVYRPDTEFGQV
YLKFTLVADLLIVSFKEK
MEKRKPHFKLELVKQAVTEQRYRFTRVALEGGAELGMEMADMLAVISALSSRDFFKSMTTYADHTTWQDVYRPDTEFGQV
YLKFTLVADLLIVSFKEK
Download Length: 297 bp
Antitoxin
Download Length: 134 a.a. Molecular weight: 14781.69 Da Isoelectric Point: 6.4554
>AT264844 WP_031306592.1 NZ_CP111110:c2839449-2839048 [Pseudomonas chengduensis]
MKCPVCGGAELVHDTRDMPFTYKGQTTQITAVTADWCDACGESLTGPAESERVMRAMNEFRQQVNAQDGNQELIRSVRKQ
LRLSQREAAELFGGGPNAFSRYERGSTEAPQPLVQLFKILGRHPELINELRAG
MKCPVCGGAELVHDTRDMPFTYKGQTTQITAVTADWCDACGESLTGPAESERVMRAMNEFRQQVNAQDGNQELIRSVRKQ
LRLSQREAAELFGGGPNAFSRYERGSTEAPQPLVQLFKILGRHPELINELRAG
Download Length: 402 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|