Detailed information of TA system TA026476

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 49038..49280
• Replicon: plasmid EF62pB
• Accession: NC_017313
• Organism: Enterococcus faecalis 62

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: EF62_RS15720
• Protein ID: WP_002360667.1
• Coordinates: 49038..49148 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	49189..49280 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EF62_RS15680 (44957)	44957..45577	+	621	WP_002366000.1	recombinase family protein	-
EF62_RS15685 (45567)	45567..45881	+	315	WP_025190469.1	hypothetical protein	-
EF62_RS15690 (45875)	45875..46099	+	225	WP_002414746.1	ultraviolet resistance protein UvrA repressor UvrC	-
EF62_RS15695 (46160)	46160..46369	+	210	WP_014524913.1	hypothetical protein	-
EF62_RS15700 (46381)	46381..46683	+	303	WP_002393766.1	DUF6440 family protein	-
EF62_RS15705 (47112)	47112..48440	+	1329	WP_002415105.1	ultraviolet resistance protein UvrA	-
EF62_RS15710 (48437)	48437..48787	+	351	WP_002406178.1	hypothetical protein	-
EF62_RS16385 (48744)	48744..48956	+	213	WP_002406179.1	hypothetical protein	-
EF62_RS15720 (49038)	49038..49148	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (49189)	49189..49280	-	92	NuclAT_0	-	Antitoxin
- (49189)	49189..49280	-	92	NuclAT_0	-	Antitoxin
- (49189)	49189..49280	-	92	NuclAT_0	-	Antitoxin
- (49189)	49189..49280	-	92	NuclAT_0	-	Antitoxin
EF62_RS15725 (49389)	49389..49685	+	297	WP_002406180.1	replication control protein PrgN	-
EF62_RS15730 (49787)	49787..50062	-	276	WP_002369783.1	DNA segregation protein PrgO	-
EF62_RS15735 (50040)	50040..50969	-	930	WP_002366009.1	ParA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	prgB/asc10	1..51104	51104

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T26476 WP_002360667.1 NC_017313:49038-49148 [Enterococcus faecalis 62]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T26476 NC_017313:49038-49148 [Enterococcus faecalis 62]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin

Nucleotide

• Length: 92 bp

>AT26476 NC_017313:c49280-49189 [Enterococcus faecalis 62]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin