Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/Fst(toxin)
Location 49038..49253 Replicon plasmid EF62pB
Accession NC_017313
Organism Enterococcus faecalis 62

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag EF62_RS15720 Protein ID WP_002360667.1
Coordinates 49038..49148 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 49189..49253 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EF62_RS15680 44957..45577 + 621 WP_002366000.1 recombinase family protein -
EF62_RS15685 45567..45881 + 315 WP_025190469.1 hypothetical protein -
EF62_RS15690 45875..46099 + 225 WP_002414746.1 ultraviolet resistance protein UvrA repressor UvrC -
EF62_RS15695 46160..46369 + 210 WP_014524913.1 hypothetical protein -
EF62_RS15700 46381..46683 + 303 WP_002393766.1 DUF6440 family protein -
EF62_RS15705 47112..48440 + 1329 WP_002415105.1 ultraviolet resistance protein UvrA -
EF62_RS15710 48437..48787 + 351 WP_002406178.1 hypothetical protein -
EF62_RS16385 48744..48956 + 213 WP_002406179.1 hypothetical protein -
EF62_RS15720 49038..49148 + 111 WP_002360667.1 type I toxin-antitoxin system Fst family toxin Toxin
- 49189..49253 - 65 - - Antitoxin
EF62_RS15725 49389..49685 + 297 WP_002406180.1 replication control protein PrgN -
EF62_RS15730 49787..50062 - 276 WP_002369783.1 DNA segregation protein PrgO -
EF62_RS15735 50040..50969 - 930 WP_002366009.1 ParA family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - prgB/asc10 1..51104 51104


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 37 a.a.        Molecular weight: 4117.92 Da        Isoelectric Point: 4.1672

>T26473 WP_002360667.1 NC_017313:49038-49148 [Enterococcus faecalis 62]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Download         Length: 111 bp

>T26473 NC_017313:49038-49148 [Enterococcus faecalis 62]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 65 bp

>AT26473 NC_017313:c49253-49189 [Enterococcus faecalis 62]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References