Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2807459..2808085 Replicon chromosome
Accession NZ_CP110921
Organism Methylococcus sp. 16-5

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag OOT43_RS13305 Protein ID WP_266021063.1
Coordinates 2807894..2808085 (-) Length 64 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OOT43_RS13300 Protein ID WP_266021062.1
Coordinates 2807459..2807815 (-) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOT43_RS13280 (OOT43_13280) 2802790..2803611 - 822 WP_266021059.1 transglutaminase family protein -
OOT43_RS13285 (OOT43_13285) 2803616..2803903 - 288 WP_266024916.1 HigA family addiction module antitoxin -
OOT43_RS13290 (OOT43_13290) 2805113..2805649 + 537 WP_266021060.1 J domain-containing protein -
OOT43_RS13295 (OOT43_13295) 2805811..2807316 - 1506 WP_266021061.1 hypothetical protein -
OOT43_RS13300 (OOT43_13300) 2807459..2807815 - 357 WP_266021062.1 HigA family addiction module antitoxin Antitoxin
OOT43_RS13305 (OOT43_13305) 2807894..2808085 - 192 WP_266021063.1 hypothetical protein Toxin
OOT43_RS13310 (OOT43_13310) 2808520..2809683 - 1164 WP_266021064.1 GGDEF domain-containing protein -
OOT43_RS13315 (OOT43_13315) 2810183..2811598 - 1416 WP_266021065.1 DUF1501 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(30-82)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7182.34 Da        Isoelectric Point: 10.7969

>T264489 WP_266021063.1 NZ_CP110921:c2808085-2807894 [Methylococcus sp. 16-5]
MIRTFAEKATDAVFAGERVRKYPAKLLQMARRILAWLDRAERIESLKVPPGNRIEALGGDRND

Download         Length: 192 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13202.34 Da        Isoelectric Point: 7.2463

>AT264489 WP_266021062.1 NZ_CP110921:c2807815-2807459 [Methylococcus sp. 16-5]
MTIRIEEINALDFCDVADPHLGKLAPIHPGEILREEFLKPLGLSVNALAQALRVPATRIHEIVKERRGITPDTALRLARY
FGGDARMWLNLQANFDLKMAARSSCIEREVIPRESTAA

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References