Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1380551..1381071 Replicon chromosome
Accession NZ_CP110921
Organism Methylococcus sp. 16-5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OOT43_RS06285 Protein ID WP_266023976.1
Coordinates 1380551..1380817 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OOT43_RS06290 Protein ID WP_266023978.1
Coordinates 1380820..1381071 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOT43_RS06260 (OOT43_06260) 1376356..1377453 + 1098 WP_266023969.1 spermidine/putrescine ABC transporter ATP-binding protein PotA -
OOT43_RS06265 (OOT43_06265) 1377437..1378288 + 852 WP_266023971.1 spermidine/putrescine ABC transporter permease PotB -
OOT43_RS06270 (OOT43_06270) 1378285..1378680 - 396 WP_266023972.1 GFA family protein -
OOT43_RS06275 (OOT43_06275) 1378704..1379516 + 813 WP_266023973.1 spermidine/putrescine ABC transporter permease PotC -
OOT43_RS06280 (OOT43_06280) 1379513..1380547 + 1035 WP_266023974.1 extracellular solute-binding protein -
OOT43_RS06285 (OOT43_06285) 1380551..1380817 - 267 WP_266023976.1 Txe/YoeB family addiction module toxin Toxin
OOT43_RS06290 (OOT43_06290) 1380820..1381071 - 252 WP_266023978.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OOT43_RS06295 (OOT43_06295) 1381122..1382201 - 1080 WP_266023980.1 aminoglycoside phosphotransferase family protein -
OOT43_RS06300 (OOT43_06300) 1382198..1382791 - 594 WP_266023981.1 DNA endonuclease SmrA -
OOT43_RS06305 (OOT43_06305) 1382873..1384387 - 1515 WP_266023982.1 B12-binding domain-containing radical SAM protein -
OOT43_RS06310 (OOT43_06310) 1384478..1385266 + 789 WP_266023983.1 zinc-dependent peptidase -
OOT43_RS06315 (OOT43_06315) 1385305..1385853 + 549 WP_266023984.1 ribosome biogenesis factor YjgA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10271.70 Da        Isoelectric Point: 9.4020

>T264484 WP_266023976.1 NZ_CP110921:c1380817-1380551 [Methylococcus sp. 16-5]
VRVIRFVPDAGEAYLYWQEQDRKTLKRINLLITAAAREPFSGLGKPEPLRGNLSGYWSRRIDDTHRLVYRATDDDLVIIA
CRFHYYGS

Download         Length: 267 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8957.18 Da        Isoelectric Point: 4.9721

>AT264484 WP_266023978.1 NZ_CP110921:c1381071-1380820 [Methylococcus sp. 16-5]
MKVVTYSHARNALKSVLDGVVQDADVTIISRRDAVVMSLEHYNSMLETLYPMSTPANAAALARAIEQDKADQAVPRELIG
DGG

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References