Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 4809975..4810669 Replicon chromosome
Accession NZ_CP110887
Organism Dickeya solani strain DsR207

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag OQ522_RS20930 Protein ID WP_022633739.1
Coordinates 4809975..4810379 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID A0A2K8VUD1
Locus tag OQ522_RS20935 Protein ID WP_022633740.1
Coordinates 4810376..4810669 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ522_RS20900 (OQ522_11655) 4805155..4806189 - 1035 WP_022633732.1 harpin HrpZ family protein -
OQ522_RS20905 (OQ522_11660) 4806350..4806760 - 411 WP_022633733.1 HrpV family type III secretion system protein -
OQ522_RS20910 (OQ522_11665) 4806757..4806945 - 189 WP_022633734.1 HrpT family type III secretion system protein -
OQ522_RS20915 (OQ522_11670) 4806980..4809049 - 2070 WP_023637836.1 type III secretion system outer membrane ring subunit SctC -
OQ522_RS20920 (OQ522_11675) 4809042..4809476 - 435 WP_022633737.1 type III secretion system chaperone -
OQ522_RS20925 (OQ522_11680) 4809463..4809690 - 228 WP_022633738.1 type III secretion protein HrpF -
OQ522_RS20930 (OQ522_11685) 4809975..4810379 - 405 WP_022633739.1 type II toxin-antitoxin system YafO family toxin Toxin
OQ522_RS20935 (OQ522_11690) 4810376..4810669 - 294 WP_022633740.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
OQ522_RS20940 (OQ522_11695) 4810887..4811936 - 1050 WP_022633741.1 hypothetical protein -
OQ522_RS20945 (OQ522_11700) 4812476..4813636 + 1161 WP_022633742.1 alpha/beta fold hydrolase -
OQ522_RS20950 (OQ522_11705) 4813647..4814960 - 1314 WP_022633743.1 lytic murein transglycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4809463..4819391 9928


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(29-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15475.86 Da        Isoelectric Point: 8.4931

>T264455 WP_022633739.1 NZ_CP110887:c4810379-4809975 [Dickeya solani]
MNIRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFK
RTSDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY

Download         Length: 405 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10934.48 Da        Isoelectric Point: 5.2082

>AT264455 WP_022633740.1 NZ_CP110887:c4810669-4810376 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8VUD1

References