Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 4810035..4810729 Replicon chromosome
Accession NZ_CP110886
Organism Dickeya solani strain DsR34

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag OQ520_RS20930 Protein ID WP_022633739.1
Coordinates 4810035..4810439 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID A0A2K8VUD1
Locus tag OQ520_RS20935 Protein ID WP_022633740.1
Coordinates 4810436..4810729 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ520_RS20900 (OQ520_11655) 4805215..4806249 - 1035 WP_022633732.1 harpin HrpZ family protein -
OQ520_RS20905 (OQ520_11660) 4806410..4806820 - 411 WP_022633733.1 HrpV family type III secretion system protein -
OQ520_RS20910 (OQ520_11665) 4806817..4807005 - 189 WP_022633734.1 HrpT family type III secretion system protein -
OQ520_RS20915 (OQ520_11670) 4807040..4809109 - 2070 WP_023637836.1 type III secretion system outer membrane ring subunit SctC -
OQ520_RS20920 (OQ520_11675) 4809102..4809536 - 435 WP_022633737.1 type III secretion system chaperone -
OQ520_RS20925 (OQ520_11680) 4809523..4809750 - 228 WP_022633738.1 type III secretion protein HrpF -
OQ520_RS20930 (OQ520_11685) 4810035..4810439 - 405 WP_022633739.1 type II toxin-antitoxin system YafO family toxin Toxin
OQ520_RS20935 (OQ520_11690) 4810436..4810729 - 294 WP_022633740.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
OQ520_RS20940 (OQ520_11695) 4810947..4811996 - 1050 WP_022633741.1 hypothetical protein -
OQ520_RS20945 (OQ520_11700) 4812536..4813696 + 1161 WP_022633742.1 alpha/beta fold hydrolase -
OQ520_RS20950 (OQ520_11705) 4813707..4815020 - 1314 WP_022633743.1 lytic murein transglycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4809523..4819451 9928


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(29-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15475.86 Da        Isoelectric Point: 8.4931

>T264440 WP_022633739.1 NZ_CP110886:c4810439-4810035 [Dickeya solani]
MNIRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFK
RTSDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY

Download         Length: 405 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10934.48 Da        Isoelectric Point: 5.2082

>AT264440 WP_022633740.1 NZ_CP110886:c4810729-4810436 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8VUD1

References