Detailed information of TA system TA026436

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 172631..172854
• Replicon: chromosome
• Accession: NC_017312
• Organism: Enterococcus faecalis 62

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: EF62_RS00840
• Protein ID: WP_075551663.1
• Coordinates: 172753..172854 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	172631..172808 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EF62_RS00815	168278..169231	-	954	WP_002354964.1	siderophore ABC transporter substrate-binding protein	-
EF62_RS00820	169270..170025	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
EF62_RS00825	170022..170987	-	966	WP_014524706.1	iron chelate uptake ABC transporter family permease subunit	-
EF62_RS00830	170984..171931	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
EF62_RS00835	172116..172568	+	453	WP_002354958.1	YueI family protein	-
-	172631..172808	+	178	-	-	Antitoxin
EF62_RS00840	172753..172854	-	102	WP_075551663.1	putative holin-like toxin	Toxin
EF62_RS00845	173186..173287	-	102	WP_075551663.1	putative holin-like toxin	-
EF62_RS00850	173476..175746	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
EF62_RS00855	175917..176417	+	501	WP_002354954.1	cysteine hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T26436 WP_075551663.1 NC_017312:c172854-172753 [Enterococcus faecalis 62]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

>T26436 NC_017312:c172854-172753 [Enterococcus faecalis 62]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA

Antitoxin

Nucleotide

• Length: 178 bp

>AT26436 NC_017312:172631-172808 [Enterococcus faecalis 62]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA

Structures

Antitoxin