Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 122849..123118 | Replicon | plasmid pHB42-F4 |
Accession | NZ_CP110815 | ||
Organism | Escherichia coli strain THB42-F4 |
Toxin (Protein)
Gene name | hok | Uniprot ID | - |
Locus tag | N0552_RS23055 | Protein ID | WP_001372321.1 |
Coordinates | 122993..123118 (+) | Length | 42 a.a. |
Antitoxin (RNA)
Gene name | sok | ||
Locus tag | - | ||
Coordinates | 122849..122914 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N0552_RS23020 | 117851..118312 | - | 462 | Protein_132 | hypothetical protein | - |
N0552_RS23025 | 118614..119141 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
N0552_RS23030 | 119199..119432 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
N0552_RS23035 | 119493..121461 | + | 1969 | Protein_135 | ParB/RepB/Spo0J family partition protein | - |
N0552_RS23040 | 121530..121964 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
N0552_RS23045 | 121961..122723 | + | 763 | Protein_137 | plasmid SOS inhibition protein A | - |
- | 122692..122916 | + | 225 | NuclAT_0 | - | - |
- | 122692..122916 | + | 225 | NuclAT_0 | - | - |
- | 122692..122916 | + | 225 | NuclAT_0 | - | - |
- | 122692..122916 | + | 225 | NuclAT_0 | - | - |
- | 122849..122914 | - | 66 | - | - | Antitoxin |
N0552_RS23050 | 122902..123051 | + | 150 | Protein_138 | plasmid maintenance protein Mok | - |
N0552_RS23055 | 122993..123118 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin |
N0552_RS23060 | 123437..123733 | - | 297 | Protein_140 | hypothetical protein | - |
N0552_RS23065 | 124033..124329 | + | 297 | WP_001272251.1 | hypothetical protein | - |
N0552_RS23070 | 124440..125261 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
N0552_RS23075 | 125558..126205 | - | 648 | WP_015059008.1 | transglycosylase SLT domain-containing protein | - |
N0552_RS23080 | 126482..126865 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
N0552_RS23085 | 127056..127742 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
N0552_RS23090 | 127836..128063 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | dfrA12 / aadA2 / qacE / mph(A) / blaTEM-1B / rmtB / aph(3')-IIa / sul2 / aph(3'')-Ib / aph(6)-Id / tet(A) / floR / blaCTX-M-55 | - | 1..162755 | 162755 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 42 a.a. Molecular weight: 4780.69 Da Isoelectric Point: 8.5110
>T264322 WP_001372321.1 NZ_CP110815:122993-123118 [Escherichia coli]
VLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAAFMAYESGK
VLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAAFMAYESGK
Download Length: 126 bp
Antitoxin
Download Length: 66 bp
>AT264322 NZ_CP110815:c122914-122849 [Escherichia coli]
GTGGACTAGACATAGGGATGCCTCGTGGTGGTTAATGAAAATTAACTTACTACGGGGCTATCTTCT
GTGGACTAGACATAGGGATGCCTCGTGGTGGTTAATGAAAATTAACTTACTACGGGGCTATCTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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