Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 183641..183863 Replicon chromosome
Accession NZ_CP110814
Organism Escherichia coli strain THB42-F4

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag N0552_RS00880 Protein ID WP_000141634.1
Coordinates 183756..183863 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 183641..183707 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0552_RS00860 179082..179984 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
N0552_RS00865 179995..180978 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
N0552_RS00870 180975..181979 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
N0552_RS00875 182009..183280 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
- 183641..183707 - 67 - - Antitoxin
N0552_RS00880 183756..183863 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
N0552_RS00885 183950..185629 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
N0552_RS00890 185626..185817 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
N0552_RS00895 185814..187385 - 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
N0552_RS00900 187658..187846 + 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
N0552_RS00905 187882..188610 + 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T264292 WP_000141634.1 NZ_CP110814:183756-183863 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT264292 NZ_CP110814:c183707-183641 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References