Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1530168..1530839 Replicon chromosome
Accession NZ_CP110790
Organism Yersinia massiliensis strain SCPM-O-B-8026 (C-146)

Toxin (Protein)


Gene name higB Uniprot ID A0A0T9T807
Locus tag OP862_RS06780 Protein ID WP_050080100.1
Coordinates 1530168..1530500 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OP862_RS06785 Protein ID WP_050080099.1
Coordinates 1530519..1530839 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP862_RS06760 (OP862_06760) 1525770..1527428 + 1659 WP_167311404.1 thiamine pyrophosphate-binding protein -
OP862_RS06765 (OP862_06765) 1527403..1528287 - 885 WP_050080103.1 LysR family transcriptional regulator -
OP862_RS06770 (OP862_06770) 1528389..1528871 + 483 WP_050080102.1 multidrug/biocide efflux PACE transporter -
OP862_RS06775 (OP862_06775) 1529040..1530011 + 972 WP_050080101.1 glucokinase -
OP862_RS06780 (OP862_06780) 1530168..1530500 + 333 WP_050080100.1 toxin Toxin
OP862_RS06785 (OP862_06785) 1530519..1530839 + 321 WP_050080099.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OP862_RS06790 (OP862_06790) 1530865..1532109 - 1245 WP_057649765.1 OFA family MFS transporter -
OP862_RS06795 (OP862_06795) 1532323..1533063 - 741 WP_050080097.1 LytTR family DNA-binding domain-containing protein -
OP862_RS06800 (OP862_06800) 1533067..1534767 - 1701 WP_167311403.1 sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(35-99)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12914.87 Da        Isoelectric Point: 10.1237

>T264244 WP_050080100.1 NZ_CP110790:1530168-1530500 [Yersinia massiliensis]
MDAVFIELPPFERVRLDYLSDDDYRTLQTALMNNPTVGDVIQQTGGLRKMRFSEAKTGKGKRSGVRVIYYWWVERFQFLL
FTIYSKGEMSDLTHSQRKILSNLLKSRKSE

Download         Length: 333 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12162.92 Da        Isoelectric Point: 8.5292

>AT264244 WP_050080099.1 NZ_CP110790:1530519-1530839 [Yersinia massiliensis]
MKKRDLFSELVEGMEAWGEANTGKKTLKTHKVSTENTVTLTSEELRHIRETLNISQALFAHYLQAGIATYQNWEQGRAKP
NKQAILLIKMVQKDPHTLHTLAELYE

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0T9T807

Antitoxin

Source ID Structure

References