Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2141255..2141778 Replicon chromosome
Accession NZ_CP110784
Organism Staphylococcus capitis strain CCSM0123

Toxin (Protein)


Gene name yoeB Uniprot ID A0A4U9THH1
Locus tag OP858_RS10500 Protein ID WP_016898859.1
Coordinates 2141255..2141521 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID C5QR06
Locus tag OP858_RS10505 Protein ID WP_002441972.1
Coordinates 2141521..2141778 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP858_RS10485 (OP858_10485) 2137845..2139107 + 1263 WP_016898854.1 cellulase family glycosylhydrolase -
OP858_RS10490 (OP858_10490) 2139246..2140253 + 1008 WP_016898855.1 efflux RND transporter periplasmic adaptor subunit -
OP858_RS10495 (OP858_10495) 2141068..2141238 - 171 WP_016898857.1 hypothetical protein -
OP858_RS10500 (OP858_10500) 2141255..2141521 - 267 WP_016898859.1 Txe/YoeB family addiction module toxin Toxin
OP858_RS10505 (OP858_10505) 2141521..2141778 - 258 WP_002441972.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OP858_RS10510 (OP858_10510) 2141941..2142339 + 399 WP_016898861.1 YolD-like family protein -
OP858_RS10515 (OP858_10515) 2142372..2142551 - 180 WP_001832816.1 CsbD family protein -
OP858_RS10520 (OP858_10520) 2143711..2144089 - 379 Protein_2039 transposase -
OP858_RS10525 (OP858_10525) 2144603..2146160 - 1558 Protein_2040 YfcC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10678.27 Da        Isoelectric Point: 10.1218

>T264227 WP_016898859.1 NZ_CP110784:c2141521-2141255 [Staphylococcus capitis]
MAKYKINIKNSAKTDLNKIKRSHLQEQFLKIVEILKYDPYQQSQSFEKLHPKHLGRYSRRINHQHRVVYTIDEENKEVLI
LAAWSHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10041.10 Da        Isoelectric Point: 4.5610

>AT264227 WP_002441972.1 NZ_CP110784:c2141778-2141521 [Staphylococcus capitis]
MKSKTPTEARKDFYQLLKRVNNDHEPVYIEGKYDESNAVIIGMEDWRSINETIYLEATGTMDKVREREHDNSGYTNIDDI
DWARL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4U9THH1

Antitoxin

Source ID Structure
AlphaFold DB A0A8B5RUG0

References