264088

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 1718234..1718772 Replicon chromosome
Accession NZ_CP110657
Organism Salmonella enterica subsp. enterica strain S2122

Toxin (Protein)


Gene name yafQ Uniprot ID M7RHM1
Locus tag OOK64_RS08680 Protein ID WP_001526148.1
Coordinates 1718234..1718509 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID M7RMV7
Locus tag OOK64_RS08685 Protein ID WP_000729713.1
Coordinates 1718512..1718772 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOK64_RS08675 (1715441) 1715441..1718146 + 2706 WP_000907029.1 HTH-type transcriptional regulator MalT -
OOK64_RS08680 (1718234) 1718234..1718509 - 276 WP_001526148.1 type II toxin-antitoxin system YafQ family toxin Toxin
OOK64_RS08685 (1718512) 1718512..1718772 - 261 WP_000729713.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OOK64_RS08690 (1718881) 1718881..1719900 - 1020 WP_000101027.1 RNA 3'-terminal phosphate cyclase -
OOK64_RS08695 (1719904) 1719904..1721118 - 1215 WP_001105521.1 RNA-splicing ligase RtcB -
OOK64_RS08700 (1721466) 1721466..1721657 - 192 Protein_1698 TROVE domain-containing protein -
OOK64_RS08705 (1721666) 1721666..1723219 - 1554 WP_000013007.1 TROVE domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10739.34 Da        Isoelectric Point: 8.8652

>T264088 WP_001526148.1 NZ_CP110657:c1718509-1718234 [Salmonella enterica subsp. enterica]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9446.80 Da        Isoelectric Point: 4.4734

>AT264088 WP_000729713.1 NZ_CP110657:c1718772-1718512 [Salmonella enterica subsp. enterica]
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SM83

Antitoxin

Source ID Structure
AlphaFold DB A0A4D6P2L2

References