26406

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 99569..100158 Replicon chromosome
Accession NC_017267
Organism Xanthomonas oryzae pv. oryzicola BLS256

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag XOC_RS00450 Protein ID WP_012443754.1
Coordinates 99877..100158 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XOC_RS00445 Protein ID WP_011260746.1
Coordinates 99569..99859 (-) Length 97 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XOC_RS00415 (XOC_0095) 94844..95320 - 477 WP_014501331.1 DUF4123 domain-containing protein -
XOC_RS00420 (XOC_0096) 95323..95757 - 435 WP_014501332.1 PAAR domain-containing protein -
XOC_RS00425 95873..96118 - 246 WP_041182989.1 hypothetical protein -
XOC_RS00435 (XOC_0097) 96454..96786 + 333 WP_011260743.1 hypothetical protein -
XOC_RS00440 (XOC_0099) 97237..98631 - 1395 WP_014501334.1 nucleoside hydrolase -
XOC_RS00445 (XOC_0101) 99569..99859 - 291 WP_011260746.1 HigA family addiction module antidote protein Antitoxin
XOC_RS00450 (XOC_0102) 99877..100158 - 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XOC_RS00455 (XOC_0103) 100253..102514 - 2262 WP_014501336.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-93)

Antitoxin

(14-68)


Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 11098.89 Da        Isoelectric Point: 10.5318

>T26406 WP_012443754.1 NC_017267:c100158-99877 [Xanthomonas oryzae pv. oryzicola BLS256]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T26406 NC_017267:c100158-99877 [Xanthomonas oryzae pv. oryzicola BLS256]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT26406 WP_011260746.1 NC_017267:c99859-99569 [Xanthomonas oryzae pv. oryzicola BLS256]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT26406 NC_017267:c99859-99569 [Xanthomonas oryzae pv. oryzicola BLS256]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5


Antitoxin

Source ID Structure

References