Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6291865..6292477 Replicon chromosome
Accession NZ_CP110389
Organism Rhodopseudomonas sp. P2A-2r

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag ONR75_RS30245 Protein ID WP_265080502.1
Coordinates 6291865..6292146 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag ONR75_RS30250 Protein ID WP_265083851.1
Coordinates 6292190..6292477 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR75_RS30230 (ONR75_30230) 6287127..6287930 + 804 WP_265080499.1 RMD1 family protein -
ONR75_RS30235 (ONR75_30235) 6287977..6288570 - 594 WP_265080500.1 hypothetical protein -
ONR75_RS30240 (ONR75_30240) 6288727..6291780 + 3054 WP_265080501.1 DNA polymerase I -
ONR75_RS30245 (ONR75_30245) 6291865..6292146 + 282 WP_265080502.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONR75_RS30250 (ONR75_30250) 6292190..6292477 + 288 WP_265083851.1 HigA family addiction module antitoxin Antitoxin
ONR75_RS30255 (ONR75_30255) 6292514..6293149 + 636 WP_265080503.1 LysE family translocator -
ONR75_RS30260 (ONR75_30260) 6293598..6295604 + 2007 WP_265083852.1 EAL domain-containing protein -
ONR75_RS30265 (ONR75_30265) 6295633..6296259 - 627 WP_265080504.1 glutathione S-transferase N-terminal domain-containing protein -
ONR75_RS30270 (ONR75_30270) 6296316..6297221 - 906 WP_265083853.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(14-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(4-58)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10577.00 Da        Isoelectric Point: 9.0518

>T263783 WP_265080502.1 NZ_CP110389:6291865-6292146 [Rhodopseudomonas sp. P2A-2r]
VIKSFKIRMTQAAFDGEALKGFPAALLKVTRRRLNYLDSATSLHDLQSPPGNRLEALKGDRQGQHSIRVNDQFRICFVWT
SEGPTDVEFVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10238.80 Da        Isoelectric Point: 7.1670

>AT263783 WP_265083851.1 NZ_CP110389:6292190-6292477 [Rhodopseudomonas sp. P2A-2r]
MHPGEVLREEFLVPLGLSAGGLAKACGVPRTRIERLANEEAGITADTALRLGKALDTSAQLWLNLQNAYDMRMAERHIGK
ELEKISPVTRSAAAA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References