Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1756792..1757382 Replicon chromosome
Accession NZ_CP110342
Organism Marinobacter sp. AN1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LJ360_RS08040 Protein ID WP_264995781.1
Coordinates 1757104..1757382 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LJ360_RS08035 Protein ID WP_264995780.1
Coordinates 1756792..1757091 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJ360_RS08010 (LJ360_08010) 1751930..1752208 - 279 Protein_1583 flagellin -
LJ360_RS08015 (LJ360_08015) 1753271..1753741 - 471 Protein_1584 flagellin -
LJ360_RS08020 (LJ360_08020) 1754095..1755561 - 1467 WP_264995777.1 aldehyde dehydrogenase family protein -
LJ360_RS08025 (LJ360_08025) 1755754..1756197 - 444 WP_264995778.1 hypothetical protein -
LJ360_RS08030 (LJ360_08030) 1756274..1756594 - 321 WP_264995779.1 hypothetical protein -
LJ360_RS08035 (LJ360_08035) 1756792..1757091 - 300 WP_264995780.1 HigA family addiction module antitoxin Antitoxin
LJ360_RS08040 (LJ360_08040) 1757104..1757382 - 279 WP_264995781.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LJ360_RS08045 (LJ360_08045) 1757535..1758506 + 972 WP_264995782.1 transposase -
LJ360_RS08050 (LJ360_08050) 1758929..1759228 - 300 WP_264995783.1 type II toxin-antitoxin system VapC family toxin -
LJ360_RS08055 (LJ360_08055) 1759230..1759454 - 225 WP_264995784.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
LJ360_RS08060 (LJ360_08060) 1759991..1760773 - 783 WP_264995785.1 enoyl-CoA hydratase -
LJ360_RS08065 (LJ360_08065) 1761017..1761492 + 476 Protein_1594 flagellin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10676.11 Da        Isoelectric Point: 8.5405

>T263621 WP_264995781.1 NZ_CP110342:c1757382-1757104 [Marinobacter sp. AN1]
MIRSFRCKETQGLFETGNTRRFSAIKNVAERKLILLQAAETLVDLKSPTGNRLEALKGDRTGQHSIRINQQWRVCFRWTD
DGPEDVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11283.92 Da        Isoelectric Point: 9.6205

>AT263621 WP_264995780.1 NZ_CP110342:c1757091-1756792 [Marinobacter sp. AN1]
MTQNGMRPIHPGEIIREDYLEPTGMSVSALSRALNVPVTRINDVVREKRGITADTALRLARYFGTSERFWLNLQMEYELR
KAQIEKGPQVNKEVQPNAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References