263609

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5121197..5121618 Replicon chromosome
Accession NZ_CP110313
Organism Xanthomonas phaseoli pv. phaseoli strain BB007a

Toxin (Protein)


Gene name higB Uniprot ID A0A3Q9Q4S9
Locus tag OM954_RS22390 Protein ID WP_017156024.1
Coordinates 5121505..5121618 (-) Length 38 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag OM954_RS22385 Protein ID WP_264685101.1
Coordinates 5121197..5121487 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM954_RS22360 (OM954_22360) 5116532..5116864 + 333 WP_003482333.1 hypothetical protein -
OM954_RS22370 (OM954_22370) 5117179..5119104 + 1926 WP_039574551.1 M61 family metallopeptidase -
OM954_RS22375 (OM954_22375) 5119172..5119351 + 180 WP_039574549.1 hypothetical protein -
OM954_RS22380 (OM954_22380) 5119454..5120842 - 1389 WP_039574546.1 type III secretion system effector XopQ -
OM954_RS22385 (OM954_22385) 5121197..5121487 - 291 WP_264685101.1 HigA family addiction module antitoxin Antitoxin
OM954_RS22390 (OM954_22390) 5121505..5121618 - 114 WP_017156024.1 hypothetical protein Toxin
OM954_RS22395 (OM954_22395) 5121615..5121788 - 174 WP_201443182.1 hypothetical protein -
OM954_RS22400 (OM954_22400) 5121883..5124390 - 2508 WP_046834789.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 5072497..5145526 73029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(14-63)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4677.41 Da        Isoelectric Point: 9.1273

>T263609 WP_017156024.1 NZ_CP110313:c5121618-5121505 [Xanthomonas phaseoli pv. phaseoli]
MKGERRGQYRIRINDRWRICVRWMEGDVVQVEIIDYH

Download         Length: 114 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10374.14 Da        Isoelectric Point: 11.0968

>AT263609 WP_264685101.1 NZ_CP110313:c5121487-5121197 [Xanthomonas phaseoli pv. phaseoli]
MTVLPNIHPGAILLEEFLQPLGISQNALARATGVPPRRIKKSVLGKRGITADTAVRLAAALGTFERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q9Q4S9

Antitoxin

Source ID Structure

References